Hypoxia- Increasing treatment resistance in tumours Hypoxia, or low oxygen levels, in the tumor microenvironment significantly contributes to treatment resistance in cancer through several mechanisms: Altered Cellular Metabolism: Hypoxic conditions lead to a shift in tumor cell metabolism from oxidative phosphorylation to glycolysis, known as…

Hyperbaric oxygen preconditioning enhances cellular resilience Hyperbaric oxygen therapy (HBOT) represents a unique method of inducing a hormetic response, wherein low levels of oxidative stress elicit adaptive changes that enhance cellular resilience. The infusion of hyperbaric oxygen increases tissue oxygen tension, leading to the production…

Oxidative Stress and HBOT Despite the wealth of evidence supporting its effectiveness, HBOT continues to be under-utilized, primarily due to a lack of awareness and misconceptions regarding its safety and applications. Oxygen is essential to life. Without oxygen CPR teach us that biological death begins…

Remembering Veterans Day 2024- HBOT making a difference Hyperbaric treatments were originally developed to address the physiological impacts of extraordinary pressure changes on the human body. However, the unique atmospheric pressures experienced by veterans in combat environments—characterized by blasts, breaching operations, and sustained firing of…