Depression-HBOT has been demonstrated as an effective potential treatment 

Depression-Hyperbaric Oxygen Therapy (HBOT) has been demonstrated as an effective potential treatment

The beneficial effects of Hyperbaric Oxygen Therapy (HBOT) have been demonstrated  in a growing number of studies for depression. Here are key points regarding the impact of HBOT on depression:

1. Mechanism of Action: HBOT may influence depression by enhancing brain oxygenation and reducing inflammation, which are factors that can contribute to depressive symptoms. Increased oxygen levels can improve neurotransmitter function and promote neuroplasticity, potentially leading to mood improvements.

2. Clinical Studies: Some clinical studies have shown that HBOT can relieve symptoms of depression and anxiety, particularly in conjunction with conventional therapies. For example, in patients with post-stroke depression, HBOT has been found to be an effective and safe therapeutic approach. The therapy has been noted to significantly relieve depression and anxiety and improve physical function in these patients.

3. Combination with Other Treatments: HBOT is often studied in combination with pharmacological treatments, such as selective serotonin re-uptake inhibitors. Some research suggests that combining HBOT with standard antidepressants medications might enhance the overall therapeutic effect.

4. Potential in Chronic Conditions: There is interest in the potential of HBOT to treat depression associated with chronic medical conditions, such as post-stroke depression or depression following other significant medical events like spinal cord injury.

5. Safety and Efficacy: While the results are promising, they should be interpreted with caution due to the relatively small sample sizes and the preliminary nature of the research.

Further studies are needed to fully establish optimal protocols in treating depression. In summary, while not a mainstream treatment for depression, studies of the use of HBOT in military veterans have consistently demonstrated statistically shown improvements in depression and satisfaction with life.  These observations highlight the potential as an adjunct therapy that might enhance the effects of conventional treatments in depressive disorders.