Traditional approaches versus The Press-Pulse Approach to Cancer Treatment
Traditional approaches versus The Press-Pulse Approach to Cancer Treatment
The Press Pulse approach differs from traditional cancer therapies in several key ways:
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Metabolic Targeting: Traditional cancer therapies, such as chemotherapy and radiation, primarily focus on directly killing cancer cells or shrinking tumours through cytotoxic effects. In contrast, the Press Pulse approach targets the metabolic vulnerabilities of cancer cells. It leverages the altered metabolism of cancer cells, which often rely heavily on glucose and have less metabolic flexibility compared to normal cells.
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Combination Strategy: The Press Pulse approach combines continuous metabolic stress (the “press”) with intermittent, targeted therapies (the “pulse”). This dual strategy aims to weaken cancer cells through metabolic stress and then apply targeted therapies to maximize their impact. Traditional therapies often use a single modality or combination of cytotoxic agents without specifically targeting metabolic pathways.
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Reduced Side Effects: By focusing on metabolic vulnerabilities, the Press Pulse approach seeks to minimize damage to normal cells, potentially reducing side effects compared to traditional therapies that can harm both cancerous and healthy tissues.
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Dietary Interventions: The Press component often includes dietary strategies, such as a ketogenic diet, to restrict glucose availability to cancer cells. Traditional therapies do not typically incorporate dietary modifications as a core component of treatment.
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Adaptive Strategy: The Press Pulse approach is adaptive, using metabolic stress to sensitize cancer cells to subsequent therapeutic pulses. This contrasts with traditional therapies that may not adjust based on the metabolic state of the cancer cells.
Overall, the Press Pulse approach represents a shift towards exploiting the unique metabolic characteristics of cancer cells, aiming for a more targeted and potentially less toxic treatment strategy.